The cardiovascular effects of Wegovy have been extensively studied, with the SELECT trial demonstrating a significant reduction in major adverse cardiovascular events in patients with established cardiovascular disease, though this is not a current UK-licensed indication
Rushing this process by starting at higher doses or escalating too quickly dramatically increases risk of severe nausea, vomiting, diarrhea, and other adverse effects that can derail treatment
Tirzepatide (Eli Lillys Mounjaro/Zepbound) is a dual GLP-1/GIP receptor agonist with four years of Phase 3 data, three FDA approvals, and a published cardiovascular outcomes trial
The increases were broadly consistent with those documented for approved GLP-1 receptor agonists in their respective SmPCs
Statistical significance in e was determined by one-way ANOVA followed by Bonferroni post-hoc analysis
The company has reported that patients using its cash-pay healthcare marketplace saved between 20% and 67% on the cost of healthcare services