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Comparing germ-free mice to conventionally grown (CONV-R) mice, it has been shown that the former had increased bone mass due to their changed immunological state, which includes lower pro-inflammatory cytokines, decreased CD4+ T cells, and fewer osteoclasts/precursors in the bone marrow (220)

Hydration: Keeps the skin hydrated and moisturized, preventing dryness and dullness for a radiant glow

Although these findings may a priori not be applicable for a proper exposure assessment in other countries, it seems plausible to estimate that normal daily intake rates via Western-style diets (not by enriched products) may not exceed 200 mg/d

10.1089/ars.2024.0586 43 JungE.JungW

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Clinical Update 8/10/2021 Best Form of B-12 for Vegans