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Retatrutide is best understood as a research-stage triple agonist with a biologically interesting mechanism and unanswered clinical questions
Melanotan 1 (afamelanotide) is a linear 13-residue analogue of alpha-MSH
10.1038/nature12328 Nature 66 LundA.BaggerJ
Gut microbiota, a new frontier to understand traditional Chinese medicines
The authors developed a selective ROCK2 inhibitor, TDI01, and report antifibrotic activity across rodent and minipig MASH models, followed by early clinical testing
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