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In the current study, the dose range was 23 g/day and there was no significant dose-dependence from l-carnitine efficacy on BMI in T2DM patients, so the lower dose of 2 g/day was selected as recommended dose

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This result approximates to the 24-h loss if there is no large body surface area deviation.69 It must be considered that there is high variability among albuminuria measurements, so to confirm the existence of pathological albuminuria, more than one sample is required.10,11 Factors that may influence albuminuria determination independent of kidney damage are exercise, infections, fever, congestive heart failure, menstruation and hyperglycemia or very high blood pressure.12 Two elevated values in three samples obtained at least three months apart are necessary to consider the presence of significant albuminuria

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