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Since GLP-1 medications slow gastric emptying, drinking large amounts of fluid with meals can exacerbate feelings of fullness and nausea
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Common side effects of GLP-1R activation within the gastrointestinal tract also include nausea, vomiting, constipation, and diarrhea, due to the receptors role in modulating gastric emptying
Melatonin rhythm in children with enuresis [PMID: 17034494] Laboratory literature summary: Melatonin rhythm in children with enuresis
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