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Clin Drug Investig
Farxiga is available in both brand-name and generic forms (generic dapagliflozin launched in 2024), whereas semaglutide (Ozempic) is only available as a brand-name medication with no generic option
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High-dose vitamin C requires caution in people with kidney disease, G6PD deficiency, or a history of kidney stones because large IV doses increase oxalate load
Changes in morbid adipose tissue in endocrine characteristics could decrease adiponectin secretion, which is an insulin enhancer ( Metabolomics revealed that APS could strengthen ISI by upregulating the mi-RNA transducer of ErbB2.2, TMEM100, and the ubiquitin-specific proteases (USP15) (Pan et al., 2019
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