Joseph Rizzo, senior author of the July 2024 study that found an association between semaglutide and NAION, called the condition, in effect, a stroke of the optic nerve. Rizzo is the director of neuro-ophthalmology at Mass Eye and Ear in Boston
The two practical considerations are gastric emptying, which is strongest when you start and increase the dose, and weight loss, reducing your levothyroxine requirement
Ask whether a slower dose escalation or a lower maintenance dose might reduce sexual side effects while preserving weight loss benefits
These issues usually go away by themselves
Mar 25, 2026 What happens if your injection day falls on the worst possible day this week
Berberine has a larger evidence base than most OTC supplements used alongside GLP-1 therapy