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Folate coenzymes act as acceptors and donors of one-carbon units in a variety of reactions critical to the metabolism of nucleic acids and amino acids ( Figure 2 ) (3)

Over a two-month period, participants received either a multi-enzyme blend derived from fungal fermentation or a placebo

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Early data are promising: retatrutide, a leading candidate in this class, produced 24.2% average weight loss at 48 weeks in a Phase 2 trial, exceeding results seen with current medications

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