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Lifestyle Adjustments to Manage GLP-1 Side Effects Beyond dietary modifications, several lifestyle strategies can help minimise bloating and improve overall tolerance of GLP-1 medications

doi: 10.3389/fnut.2025.1654911 Received 27 June 2025 Accepted 24 July 2025 Published 05 August 2025 Volume 12 - 2025 Edited by Pangzhen Zhang, The University of Melbourne, Australia Reviewed by Jata Shankar, Jaypee University of Information Technology, India Santino Orecchio, University of Palermo, Italy Updates Copyright 2025 Noreen, Sultan, Hashmi, Aja and Atoki

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Conclusion: FOXO4-DRI promotes the nuclear export of phosphorylated P53 by inhibiting the binding of FOXO4 to P53 in endothelial cells, thereby facilitating the apoptosis of senescent endothelial cells and alleviating aging

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