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Introduction# CagriSema and retatrutide represent two of the most anticipated next-generation obesity treatments, each taking a fundamentally different multi-target approach to weight management
Genetic instruments for GLP-1R activation were selected based on associations with traits linked to drug target effects, such as body mass index (BMI) and glycated hemoglobin (HbA1c)
Overexpression of ferroptosis defense enzyme Gpx4 retards motor neuron disease of SOD1G93A mice
Solvent effects were included using a polarizable continuum model (PCM)
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