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The N-terminal GSDMD fragment creates transmembrane pores, leading to the initiation of pyroptotic cell death
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The exact dose-per-actuation for this device is printed on the pen label and instructions for use (IFU)
Costs can vary widely depending on: Dose strength Route of administration (IM vs IV) Physician oversight fees Pharmacy dispensing charges Programs typically range between $100$300 per month for weekly injections
Diabetes Obes Metab 18:186190
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