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Immunosenescence, a process of immune system dysregulation, causes the elderly to produce low-affinity immunoglobulins at an increased rate, leading to elevated serum levels of IgG1 and IgG4 (124)
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doi: 10.1038/npp.2012.25 29 D'AmicoR.ImpellizzeriD.CuzzocreaS.Di PaolaR
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