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To identify potential off-target substrates, we searched enriched motifs against the human proteome, using the enrichment score of the IL-1 motif (cleavage between Glu 18 and Asp 19) as the cutoff for predicted cleavage activity (Fig

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7 Discussion Current research suggests a close relationship between glucose metabolism disorders and energy conversion disorders and PD pathogenesis

Microdosing a GLP-1 medication is an individual decision that warrants consideration of several factors such as medical history, weight loss goals, financial constraints, and each patients ability to manage off-label dosing instructions and guidelines

Accepting some unknowns in terms of safety is reasonable for life-changing medication