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This, in turn, stimulates downstream signaling elements dependent on both protein kinase A (PKA) and exchange protein directly activated by cAMP (EPAC) activation, which triggers the opening of voltage-dependent calcium channels (VDCCs), resulting in insulin exocytosis [24, 25]
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A three-point temperature calibration was performed of the cooling stage to verify the accuracy of the recorded temperature for our experiments using n -dodecane, n -undecane, and n -decane 32,51
The secretion of intrinsic factor is stimulated by all three of the mechanisms that lead to gastric acid secretion: histamine, acetylcholine, and gastrin