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MRS data acquisition and analysis Spectra were obtained on a 3T GE Discovery MR750 (SW: DV26 R01) scanner from two regions of interest: anterior cingulate cortex (ACC) and left dorsolateral prefrontal cortex (DLPFC) (Figure 1)

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and J Trop Pediatr

In its hyphal state, Candida produces specialised invasins and proteinases including candidalysin, a peptide toxin that physically puncture intestinal epithelial cells, widen tight junctions between cells, and allow the yeast itself and its toxic metabolites to translocate into the bloodstream and lymphatic system

Another mechanism is that a previously formed ubiquitin chain serves as a foundation for K48-linked branching, contributing to efficient K48-linked chain assembly 8,10