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the overall 12-month discontinuation rate for GLP-1 agonists is estimated at 36.5%, with higher rates observed in patients with obesity alone compared to those with type 2 diabetes
Strengths and Limitations of Clinical Trial Although there is substantial evidence supporting the occurrence of oxidative stress in individuals with T21 throughout various stages of development, clinical trials conducted thus far have not yielded significant advancements in clinical management for this condition (S
Treatment with various antioxidants has been tried against the increased oxidative stress in DS
For example, a patient struggling with obesity and poor postprandial control may benefit more from semaglutide than other agents
Many patients report improvement over time, though some continue to experience intermittent symptoms throughout treatment
Participants will complete check-ins through video chats and wear a monitoring device, similar to a Garmin watch, to track their weight
