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Tirzepatide is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

There is currently no official link established between GLP-1 medications and the development or exacerbation of IBS specifically, as IBS is a functional disorder rather than a structural disease

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These include: Vegetarians and vegans- Because animal products are the primary source of Vitamin B12, people who do not eat animal products can be at risk for B12 deficiency

13 In the FDA Adverse Event Reporting System database, 73 cases of ketoacidosis in patients with T1DM or T2DM were reported from March 2013 to May 2015

However, there are significant safety considerations and clinical steps to navigate first