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Conversely, those experiencing diarrhoea or loose stools may need to temporarily moderate insoluble fibre intake whilst maintaining adequate soluble fibre to support gut health

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[86] found that semaglutide, as a GLP-1 analog, can directly act on fat cells, increase the expression of thermogenic genes for browning phenotype maintenance, improve the expression of UCP1, mitochondrial biosynthesis and thermogenic marker, thereby contributing to weight loss

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