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Through IPTW adjustment, the confounding factors were well balanced between the two groups

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And with a tolerability profile observed to date in line with a routine upper endoscopy, this is the kind of durable, procedure-based approach I could see fitting naturally into how we care for these patients. GLP-1 medicines have transformed obesity care, but they were never designed to be taken forever, and the field's answer so far has been to keep patients on a drug indefinitely

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You need diet optimization , exercise strategies , or potentially a dose adjustment

J Biol Chem 2012;287:38733884