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The material is provided as a lyophilized reference powder in sealed vials and is used for reproducible, standardized laboratory studies under controlled conditions
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Researchers isolated this specific fragment because it demonstrated the most potent biological activity among all the fragments tested
Seveljevic-Jaran et al., 2006
Always gently swirl or roll the vial between your palms
The first option has for instance been explored by targeting B cells in gMG, RA (NCT00931086), ITP, CIDP, Sjgrens syndrome (NCT03154385, NCT02531538, NCT03905525), and TED (NCT00212726) [383, 384] with therapeutic mAbs directed against CD20, B-lymphocyte stimulator protein, and CD40
The pericytes are thus involved in the maintenance and modulation of the BBB, while also modulating processes like the cerebral blood flow, neuroinflammation or the vascular development
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