The compound has been found to operate in the postrema and nucleus of the hindbrain solitary tract in order to both induce satiety and regulate appetite by acting on receptors found in the laterodorsal tegmental nucleus, ventral tegmental area, and the hypothalamus [1]
Clinical manifestations
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Consensus values and weighting factors
2.5 Quality assessment and risk of bias In line with PRISMA guidelines, the assessment of methodological quality was conducted to evaluate the strength of evidence, recognising that methodological limitations may introduce bias
Voerman E, Santos S, Patro Golab B, Amiano P, Ballester F, Barros H, et al