For example, you know, if a patient has obesity and sleep apnea, that could be a reason why it's covered
Understanding the mechanism of drug action enables physicians to best pair it up with the appropriate patients
However, it is yet to be approved for any indications beyond glycemic control
Currently, there is only one drug in this class of medicationstirzepatide, which is approved as Mounjaro for treatment of Type 2 diabetes and as Zepbound for the treatment of obesity
Potential muscle-related benefits: Increased appetite (helpful in calorie-surplus phases) Elevated growth hormone Possible preservation of lean mass In a two-year randomized, placebo-controlled trial of the oral ghrelin mimetic MK-677 in older adults, daily dosing significantly increased pulsatile growth hormone and IGF-1 levels to those of younger adults and increased fat-free mass versus placebo, suggesting enhanced protein-accruing pathways that could help preserve lean body mass
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