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The primers for PCR are listed in Table 3

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In cancer, however, DDR exerts a paradoxical influence: while repair deficiencies promote mutagenesis and tumorigenesis, restoration or hyperactivation of DDR pathways in established tumors fosters resistance by enabling efficient repair of therapy-induced DNA damage

doi: 10.1111/hel.12881 94 WroblewskiLEChoiEPetersenCDelgadoAGPiazueloMBRomero-GalloJet al

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The exercise-mimetic angle also deserves continued development