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Patients who receive weekly lipotropic injections without dietary structure or GLP-1 medication support see minimal weight change because the injections optimise a pathway (hepatic VLDL export) that requires substrate (mobilised fat from adipose tissue) to function
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Patients with rapid baseline gastric emptying (a condition sometimes called gastroparesis inverse, or dumping syndrome predisposition) may not experience the same satiety signal because food clears the stomach before the GLP-1R-mediated slowdown can accumulate
Arch Phys Med Rehabil 1986;67:436-9
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Biochem Biophys Res Commun
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