Outcomes in cardiometabolic risk GLP1R expression has been detected at low levels in human atria and ventricles, both in cardiomyocytes and endothelial cells, though its precise localization remains unclear due to limitations in antibody specificity and differences at species level [93]
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These properties of GLP-1 addressed both the inadequate insulin secretion and the hyperglucagonaemia characteristic of type 2 diabetes, known to underlie the pathophysiology of hyperglycaemia