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Administration of GLP-1 and exendin-4 promoted neurite outgrowth in cultured dorsal root ganglion (DRG) neurons, presumably explaining the increased nerve fibers observed in biopsies of IBS individuals [51]
Tirzepatide (Zepbound / Mounjaro) targets both GLP-1 and GIP receptors, offering a dual-action approach that clinical trials show may lead to even greater weight loss
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Company Announcements: Ozempic (semaglutide) approved in the US
Disla E, Rhim HR, Reddy A, Karten I, Taranta A
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