349 Similarly, mutations in valosin-containing protein (VCP), a multifunctional AAA-ATPase essential for extracting ubiquitinated proteins from cellular structures and directing them toward degradation, cause multisystem proteinopathies that include ALS, FTD, and inclusion body myopathy
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Female patients exhibited dramatically higher total reactive oxygen species (ROS) and mitochondrial calcium levels, correlating with the hyperproliferation of memory T cells
ACS Omega 8(10):93569363 Schwarz M, Lser A, Cheng Q, Wichmann-Costaganna M, Schdel P, Werz O, Arnr ES, Kipp AP (2023) Side-by-side comparison of recombinant human glutathione peroxidases identifies overlapping substrate specificities for soluble hydroperoxides