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The anti-obesogenic effect of GLP-1RAs is mediated by direct inhibition of the feeding center and indirectly through modulation of energy expenditure (Jepsen and Christensen 2021)
Follow the Prescribed Dose-Escalation Schedule One of the most important ways to reduce gastrointestinal side effects is to follow the dose schedule prescribed by your healthcare provider
Thats part of what makes this research so compelling: Evidence on GLP-1 drugs and on the benefits of improving insulin sensitivity and reducing inflammation more broadly suggests that getting ahead of metabolic issues, such as type 2 diabetes, early could help people stay healthier as they age
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