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Preclinical research demonstrated that SS31 protects against mitochondrial dysfunction across multiple disease models including heart failure, ischemiareperfusion injury, neurodegeneration, chronic kidney disease, and agerelated muscle atrophy [9]

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doi:10.1056/NEJMoa2107519

pastoris secreted recombinant DSIP-CBBBP on neurotransmitter levels, we quantified the concentrations of melatonin, serotonin, dopamine, and glutamate in the mouse serum