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It lowered pain and helped improve function with no side effects

measurable body fat reduction) Key requirement: Caloric deficit or maintenance calories with adequate protein

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Systemic vascular structure and function Though it remains unclear whether reductions in CBF or cerebral metabolism occurs first in the ADRD cascade, mechanical factors such as systemic and cerebral arterial stiffening are additional early stage vascular markers implicated in cerebral hypoperfusion in older adulthood beyond the typical effects of aging (Mitchell, 2011