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B12 supplements can interact with certain medicines, including: Chloramphenicol (Chloromycetin Sodium Succinate) Proton pump inhibitors Metformin (Glucophage, Glumetza, Riomet) Gastric acid inhibitors If youre taking any of these medications, talk to your doctor or pharmacist before starting a B12 supplement
This helps reduce bleeding risk and avoids problems with sedation or anesthesia
Nasal mucosa contains aminopeptidases and other proteases that cleave peptide bonds before the molecule can cross the epithelium
I recheck homocysteine at 4 to 6 weeks after starting supplementation
Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use
