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Adiponutrin, a transmembrane protein corresponding to a novel dietary- and obesity-linked mRNA specifically expressed in the adipose Lineage
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The review positioned 5-Amino-1MQ and combined use with NAD+ precursors such as NMN as the primary research directions for investigating NNMT-targeted cardiovascular metabolic interventions in pre-clinical models
This work established the broader significance of NNMT in methylation-dependent cellular processes and provided context for the development of selective inhibitors [3]
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