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These data highlight the dual action of DPP-4 inhibition, which targets both GLP-1 and GIP to improve glucose homeostasis

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Eligibility under TA875 generally requires a BMI of 35 kg/m or above (or 3034.9 kg/m in certain higher-risk groups) alongside at least one weight-related comorbidity, and treatment is currently recommended for up to two years within a specialist service