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CD44v9 interacts with xCT [also known as solute carrier family 7 member 11 (SLC7A11)], a cystine/glutamate transporter, for cystine uptake (5052)

By inhibiting calcium influx, exendin-4 reduces the calcium overload, which leads to apoptosis and excitation-induced neurotoxicity in RGCs, promoting RGC survival and function in DR (Wang et al., 2023)

Some pre-filled pen devices include features to help monitor injection history

Important: Although the study involved human subjects, its outcomes are not intended to imply any therapeutic claims

Covers MC4R mechanism, Vyleesi trial data, dosing, and side effects

The combination has not shown any emergent toxicity beyond what would be expected from either peptide individually