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Several molecules are currently available on the market, with partially different mechanisms of action, indications, dosages, and routes of administration (Table 1)
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doi: 10.1210/jc.2017-01210 52 HjelholtAJCharidemouEGriffinJLPedersenSBGudiksenAPilegaardHet al
Plaintiffs argue that manufacturers could have developed safer formulations or conducted more extensive pre-market testing to identify vision-related risks
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Lastly, while APOE effects dominated brain profiles, sex effects were more prominent in the periphery, which was also in accordance with a previous study in older (16 months old) APOE-TR mice (Shang et al., 2020), suggesting that regardless of age APOE has a major effect on brain bioenergetics
