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The least COX-2 expression occurred in the diclofenac sodium group and the 1.3 bis( p -Hydroxyphenyl)urea at doses of 100 and 200 mg/Kg BW

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They are the most frequently reported adverse events across every clinical trial conducted to date

Child-Pugh A (mild impairment): Begin at 200 mcg subcutaneously once daily

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It is not approved to diagnose, treat, cure, or prevent any condition