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Phytoestrogens and their human metabolites show distinct agonistic and antagonistic properties on estrogen receptor (ER) and ER in human cells
Moreover, another study also highlighted the important role of Faecalibacterium in producing butyrate (Tanca et al., 2017)
The classes that cannot be differentiated using these signatures are GSTLs and GHRs which usually exhibit VP and ES motives, and DHARs and mPGES-2 which have VP and DS motives
Luo M, He H, Kelley MR, Georgiadis MM
Available at: fda.gov
(2023) 9:eadi4862
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