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Discontinuation rates due to gastrointestinal adverse effects ranged from 47% across clinical trials, as reported in the FDA prescribing information, indicating that while nausea and vomiting are common, they are tolerable for most patients

Its available as an injectable medication or an oral medication

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Some reports suggest that policy changes in 2026 may introduce Medicare coverage for GLP-1 drugs for obesity and related comorbidities

Previous or planned (during the trial period) obesity treatment with surgery or a weight loss device