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Subacute effects of the brominated flame retardants hexabromocyclododecane and tetrabromobisphenol A on hepatic cytochrome P450 levels in rats
As the cells become weaker, they become more vulnerable to damage or apoptosis (cell death) from even small reductions in perfusion, which can occur if the individual becomes dehydrated or overheated, undergoes surgery, has a drop in blood pressure, engages is excess physical activity, has untreated sleep apnea, or experiences a traumatic shock
Start slowly and increase duration as weight loss improves exercise capacity
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Other side effects reported less commonly include mild headaches (especially during the first two dose levels), fatigue during the initial adjustment period, and occasional dizziness
The UMIN and jRCT databases will contain detailed information regarding the study
DOI: 10.1007/s00394-014-0706-z
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