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Sudden changes in the diet, especially increased or excessive grain consumption, can decrease the PH in the rumen and disturb the thiamine production of the microorganisms there
Muscle cramping (rare)
Monthly B12 injections must be administered under proper medical supervision [20]
There is no published human safety or efficacy data, no reproductive- or developmental-toxicology research, no studies in hepatic or renal impairment, and no drug-interaction studies
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