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The study also demonstrated the protective effect of exenatide on islet-cell function during GCs therapy, providing early evidence for using GLP-1 RAs to counteract the diabetogenic effects of GCs (34)
Plasma concentrations of amylin (active), C-peptide 2, ghrelin, GIP (total), GLP-1 (active), glucagon, insulin, leptin, PP, PYY, resistin, and secretin were measured in duplicate by Eve Technologies using a commercially available Mouse Metabolic Hormone 12-Plex Discovery Assay (MilliporeSigma) according to the manufacturers protocol on a Luminex 200 system (Thermo Fisher Scientific)
Science 369 , 718724 (2020)
Ultrasound confirms diagnosis, and treatment ranges from watchful waiting to cholecystectomy depending on severity
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