The primary amine groups serve as functional sites for conjugating ligands for targeting, cleavable cross-linking agents, and steric stabilizers
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Many patients share similar concerns: their appetite feels difficult to control, their weight comes back quickly, or their blood sugar remains high even when they are trying to make healthier choices
In prostate cancer, emodin treatment causes necroptosis-mediated cell death by stimulating the expression of HSP90 and PGAM5, a central modulator of mitochondrial fission, leading to the massive generation of ROS and necroptosis (Zhou et al., 2023)
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Most kidney problems linked to GLP-1s are caused by dehydration and improve once fluids are replaced