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Whilst exact mechanisms remain unclear, a combination of risk factor reduction in improved HbA1c, weight, metabolic profile, as well as direct effects of GLP-1 agonism on coronary endothelial function and improved microvascular perfusion is likely at play

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doi: 10.1016/j.mito.2015.06.002

The timeline for starting a GLP-1 after weaning depends on a few factors, including how recently you delivered, how your recovery is going, whether your postpartum hormones have stabilized, and whether you meet the clinical criteria for a GLP-1 prescription

It notes that the benefit of a dual agonist depends partly on GIP receptor function, so the second pathway is not a uniform bonus for everyone