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Another contributing mechanism to melatonins anti-amyloidogenic effects may involve the enhanced clearance of A from the brain

This regulatory interplay enhances the activation of IRF3 and IRF7, initiating type I IFN-associated innate immune responses, while simultaneously amplifying NF-B-driven inflammatory pathways, thereby fine-tuning the immune response (Fig

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Quantification of CD45 H -scores in tumours described in (c)