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doi: 10.7150/thno.56598 126 ZhangQHuYHuJEDingYShenYXuHet al

Importantly, FB23-2, a small-molecule inhibitor of FTO, selectively inhibits the m 6 A modification of ankyrin repeat and SOCS box containing 2 (ASB2) mRNA, resulting in the upregulation of ASB2, which decreases mitochondrial membrane potential, thereby triggering intracellular signaling pathways that culminate in cytoplasmic vacuolization and paraptotic cell death [95, 123]

Sex- and age-dependent activity of glutathione (GSH) peroxidase in reproductive organs in pre- and post-pubertal cattle in relation to total antioxidant capacity

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It plays a key role in immune function and protects the bodys tissues from environmental toxins