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Peptide-bond modified glutathione conjugate analogs modulate GSTpi function in GSH-conjugation, drug sensitivity and JNK signaling
it moves through a cycle, with a long growth phase, a short transition phase, and a rest phase before shedding happens
Glutathione serves as the primary substrate for the glutathione peroxidase (GPx) enzyme family, which neutralizes hydrogen peroxide and lipid hydroperoxides
The experimental trail included a 26-week treatment period, a dose-escalation period of up to 6 weeks, and a 6-week follow-up period after the end of treatment
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