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Since intense oxidative stress leads to severe damage of biomolecules, triggering cell death, it is easily understood that GSH metabolism might be upregulated in tumor cells to protect them from damage of oxidant and even promote cancer cell proliferation and metastasis

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after the FDA lifted a full clinical hold it had placed on the Investigational New Drug Application for PGN-EDODM1

1 Se considera el principal antioxidante del cuerpo porque protege la actividad celular desde el interior de las clulas, pero tambin regenera otros antioxidantes y acta como cofactor de muchas enzimas

These results suggest that IGF-1R modulates brain glucose metabolism by inhibiting the activity of GLUT1 in astrocytes [44]

F 1 generation hybrid plants originating from these parents (CEMK-9 and NahG or TRI-2 and NahG) showed an intermediate HR phenotype similar to that in wild type tobacco with normal GSH and SA levels