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Patients with diabetes should also be aware that rapid improvement in glycemic control with any medication may be associated with temporary worsening of diabetic retinopathy in some cases, highlighting the importance of regular eye examinations per American Diabetes Association guidelines
The peptide releases acetyl-SDKP (N-acetyl-seryl-aspartyl-lysyl-proline), an anti-inflammatory fragment that reduces fibrosis and modulates inflammatory responses
doi: 10.1001/jama.2023.19574
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However, there are concerns about whether semaglutide can cause hyperthyroidism
