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It may help reduce oxidative stress, which occurs when theres an imbalance between free radicals and your bodys ability to fight them off

Research has indicated that compounds targeting TRP channels, such as vanillin, capsaicin and capsazepine, can reduce reactive astrocyte activity, which in turn can mitigate A toxicity in the early stages of AD 154

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205 Currently, three major categories of SIRT1-targeted drug candidates are under investigation: natural products, synthetic small-molecule activators, and NAD + precursor supplements

Similarly, supplementation with Lactobacillus [79] and Bifidobacterium [87] modulated DA in the prefrontal cortex [79] and in the gut [87] as well as NA [87]