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More recently, a 2011 trial involving more than 35,500 men over 50 found that large doses of vitamin E increased the risk of prostate cancer by 17 percent

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Regulation of the inhibitory effects of IGF-1 on AngII-induced cardiac fibrosis by Akt-, and ROCK2-dependent signaling pathways IGF-1 inhibited myofibroblast differentiation, as demonstrated by decreased SMA protein expression in AngII-treated adult rat cardiac fibroblasts (Fig

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